Alpha testosterone, also known as α-testosterone, is a naturally occurring steroid hormone and androgen. It plays a vital role in the development and maintenance of male reproductive tissues as well as promoting secondary sexual characteristics in men. Alpha testosterone is synthesized primarily in the testes and is responsible for sperm production and development.
Some key facts about alpha testosterone:
- Alpha testosterone is the most abundant and potent naturally occurring androgen. It is estimated to account for around 95% of the testosterone in men. The remaining 5% consists of the related androgens beta testosterone and delta testosterone.
- The production of alpha testosterone begins during puberty and peaks in the late teens to early 20s. Levels slowly decline with age, dropping around 1% per year after age 30. Low alpha testosterone levels can lead to hypogonadism.
- In addition to the testes, alpha testosterone is produced in small amounts by the adrenal glands. The hypothalamus and pituitary gland regulate testosterone production through a negative feedback loop.
- Alpha testosterone circulates in the blood 98% bound to proteins like albumin and sex hormone-binding globulin. Only 1-2% remains free and bioavailable to tissues.
- The biological effects of alpha testosterone are mediated by its binding to and activation of the androgen receptor, influencing DNA transcription and protein synthesis.
Alpha testosterone is responsible for many of the physical and psychological attributes associated with masculinity and male development:
- During puberty, alpha testosterone stimulates growth of the penis and testes, promotes deepening of the voice, increases bone size and muscle mass, stimulates growth of facial and body hair, and activates sebaceous glands in the skin.
- Alpha testosterone plays a key role in sperm production (spermatogenesis) and the development of secondary sex characteristics. It supports libido and erectile function.
- The hormone has anabolic effects on protein synthesis and nitrogen retention. This leads to increased strength capacity and lean body mass.
- Alpha testosterone influences behaviors and brain function. It has been linked to aggression, risk taking, spatial abilities, and competitiveness.
- Balanced levels of the hormone support cardiovascular health, bone mineral density, fat distribution, and emotional wellbeing in men.
Measuring alpha testosterone levels through blood work is important for diagnosing clinical conditions like hypogonadism, delayed puberty, and infertility in men. Levels normally range from 300-1000 ng/dL depending on age.
If you're a man over 30 concerned about low T levels, the hormone experts at The Hormone Hub can help. Our clinics specialize in customized testosterone replacement therapy to restore healthy hormonal balance. Get back to feeling your best with an evaluation of your alpha testosterone and expert hormone optimization. Contact us today to learn more about our men's health and wellness programs.
In summary, alpha testosterone is the predominant male sex hormone responsible for the proper development and maintenance of male characteristics and reproductive function. All men require balanced levels of this vital androgen for optimal health. Signs of low alpha testosterone include reduced muscle mass, low energy, erectile dysfunction, and emotional changes. Precision hormone testing and replacement under a doctor's care may help restore normal levels. The Hormone Hub provides cutting edge testosterone therapy for men with low T. Contact us to find out more and take control of your vitality.
