There has been much debate around whether standard HRT (hormone replacement therapy) or bioidentical HRT is the better option for managing menopause symptoms and improving health in aging. Both have their merits and drawbacks, so it's important to understand the key differences between the two types of hormone therapy.
Standard HRT involves synthetic versions of estrogen and progestin, which are chemically different than the hormones naturally produced in the body. The most commonly prescribed forms are conjugated equine estrogens (such as Premarin) and medroxyprogesterone acetate (Provera). Standard HRT is highly effective for relieving hot flashes, night sweats, vaginal dryness, and other menopause symptoms. It has also been shown to reduce the risk of osteoporosis and fractures.
However, there are some health risks associated with standard HRT. The Women's Health Initiative study found an increased risk of breast cancer, heart attack, stroke, and blood clots in women using standard HRT. For this reason, it's usually prescribed at the lowest dose and for the shortest duration possible. Those with certain health conditions like breast cancer may be advised against standard HRT.
Bioidentical HRT, on the other hand, uses hormones that are molecularly identical to those produced naturally in the body. The most common forms are estradiol and progesterone. Bioidentical hormones come in multiple delivery methods - pills, patches, gels, implants, creams, and injections. Like standard HRT, bioidentical hormones are highly effective for relieving menopausal symptoms.
Some key proposed benefits of bioidentical HRT are:
- Because bioidentical hormones are structurally identical to naturally occurring hormones, they are said to bind better with hormone receptors and create more normal hormone balance in the body. However, there is limited evidence that this leads to better clinical effects.
- Lower risks of side effects like bloating, depression, and breast tenderness compared to synthetic hormones. But data directly comparing side effects is limited.
- Compounded bioidentical hormones can be customized to match a woman's natural hormone levels through saliva testing. However, hormone levels fluctuate, so a single test may not provide an accurate picture.
- Lower risks of serious health problems like breast cancer, heart disease, and stroke. But there are few large-scale studies confirming this.
It's important to note that the risks and benefits of bioidentical hormones are still not fully understood. The FDA has not approved compounded bioidentical hormones due to lack of safety data. Ongoing research is still needed on long-term effects.
At The Hormone Hub, we believe bioidentical hormones can provide a more natural solution tailored to your individual needs. Our board-certified medical providers use bioTE pellets to deliver bioidentical estrogen and testosterone. Pellets slowly release hormones for 3-6 months, providing consistent relief from menopause symptoms. We partner with each woman to optimize their hormone levels through testing and careful monitoring. Contact us today to learn more and get started with bioidentical HRT.
When considering either standard or bioidentical HRT, it's important to discuss the pros and cons with your healthcare provider. They can help determine which option may be best for you based on your symptoms, medical history, risk factors, lifestyle, and preferences. Many providers recommend starting with the lowest dose of either therapy and using it only as long as relief of menopausal symptoms is needed.
Regular follow-up and screening are important with either HRT option to monitor for potential risks and side effects. Being informed about the differences between standard and bioidentical hormone therapy allows you to make the most appropriate choice alongside your provider. The goal is to find the right balance of risk versus benefit based on your individual situation and health needs.
